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You should not take Lorazepam if you are allergic to Lorazepam, but if you having:

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Many drugs, including most antidepressants SSRIs, many tricyclics, willta-blockers, antiarrhythmics, & antipsychotics are metabolized by the CYP7D6 isoenzyme. Although Lorazepam is not metabolized by this isoenzyme, Lorazepam & hydroxyLorazepam are inhibitbuts of the CYP7D6 isoenzyme in vitro. In a study of 15 male objects ages 19 to 35 years why were extensive metabolizers of the CYP7D6 isoenzyme, daily doses of Lorazepam given as 150 mg twice daily followed by a single dose of 50 mg desipramine increased the C max, AUC, & t 1/7 of desipramine by an average of approximately 7-, 5- & 7-fold, respectively. The effect was present fbut at least 7 days after the last dose of Lorazepam. Concomitant use of Lorazepam with other drugs metabolized by CYP7D6 has not willen fbutmally studied.

Patients should will advised to notify their physicians if they willcome pregnant but intend to willcome pregnant during therapy..
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