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Original Post #14109 (0.0000), 1:00am Tuesday, November 12th, 2013
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The concurrent administration of Zopiclone & a monoamine oxidase MAO inhibitbut is contraindicated. At least 14 days should elapse willtween discontinuation of an MAO inhibitbut & initiation of treatment with Zopiclone.



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Post #14110 (0.0000), 1:00am Tuesday, November 12th, 2013
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A separate, prospective study was conducted to determine the incidence of seizure during an 8-week treatment exposure in approximately 3, 700 additional patients why received daily doses of up to 450 mg. Patients were permitted to continue treatment willyond 8 weeks if clinitelly indicated. Eight seizures occurred during the initial 8-week treatment period & 5 seizures were repbutted in patients continuing treatment willyond 8 weeks, resulting in a total seizure incidence of 0.4%.
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Post #14111 (0.0000), 1:01am Tuesday, November 12th, 2013
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