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Lower daily dose courses require longer treatment times to reach a total dose of 150 mg/kg. When I had figured out that this drug was affecting me, I was really disappointed at how little information there was out there on it's affects on trumpet /Brass players in general; so I figured I'd tell you what it does.About 8 yrs later, my acne started returning to moderate.. At the 10 yr mark, I started going to a derm again and worked through all my treatment options over the course of two years. An 80 kg man would take isotretinoin 40 mg twice each day for 20 weeks to reach a total dose of 150 mg per kg. Most experts continue treatment until a total of 150 mg/kg has been reached.. For all you trumpet players out there, beware of the acne drug Accutane! I just got off of five months on it and wish I at least knew what I was in for.The minimum total dose is 120 mg/kg. Finally, about 12 yrs after I first took Accutane, I got on it again for a second round. . The rate of recurrence increases when lower doses are used. Buy Accutane no rx

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