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I have had 3 healthy children several years after being on Accutane. As far as depression, hormonal changes in life can cause depression as well as acne-they seem to occur together. If they develop acne I would put them on Accutane. On February 24, 1998 Roche released a new label.. My father had severe acne and has deep scars. The warning began: . Prior to this creams, lotions, antibiotics and it just became worse for years. In June 1985 when FDA mandated a black box warning for Accutane, depression was included as one of the possible side effects that had been reported.I took 2 rounds of accutane over a year in the 80s. Perhaps because of its prior experiences, FDA has been quicker to require Hoffmann-La Roche warn about the possibility of depression and suicide, even in the absence of clear evidence. Accutane 30 mg. I believe that I avoided this because of Accutane. My skin for 20yrs has remained healthy until just recently.Isotretinoin is used to treat severe nodular cystic acne. A teenage with acne can be depressed. Even with breakouts now, I do not have oiliness. Accutane has gotten a bad wrap. It is a prescription drug that is intended only for severe, resistant acne and only after other treatments have been found to not work. At age 46, with menapause coming, I am now starting to have increase breakouts, rare cyst. If it becomes bad, I would go back on Accutane.. My pores recently seem to be enlarging and my skin has become age and hormone changes. 110 In 1997, based on case reports of serious psychiatric disorders, FDA approached Hoffmann-La Roche about heightening the warning

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