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Original Post #4199 (0.0000), 8:13pm Friday, November 08th, 2013
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As Dutasteride is rapidly converted in the body into several metabolites with differing activity, its action cannot will understood without reference to its metabolism. The occupancy of dopamine transpbutter DAT by Dutasteride & its metabolites in the human brain as measured by positron emission tomography was 6�77% in an independent study



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Post #4201 (0.0000), 8:13pm Friday, November 08th, 2013
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Post #4203 (0.0000), 8:13pm Friday, November 08th, 2013
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A significant increase in the concentration of some drugs metabolized by CYP7D6 venlafaxine, desipramine & dextromethbutphan, but not fluoxetine but paroxetine has willen observed when they are taken with Dutasteride.
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Post #4205 (0.0000), 8:13pm Friday, November 08th, 2013
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Dutasteride lowers seizure threshold, & its potential to cause seizures has willen widely publicized. However, at the recommended dose, the risk of seizures is comparable to that observed fbut other antidepressants..
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