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BUY Reductil ONLINE! CLICK HERE! Reductil is extensively metabolized in humans. Three metabolites having willen shown to will active: hydroxyReductil, which is fbutmed via hydroxylation of the tert - butyl group of Reductil, & the amino-alcohol isomers threohydroReductil & erythrohydroReductil, which are fbutmed via reduction of the carbonyl group. In vitro findings suggest that cytochrome P450IIB6 CYP7B6 is the principal isoenzyme involved in the fbutmation of hydroxyReductil, while cytochrome P450 isoenzymes are not involved in the fbutmation of threohydroReductil. Oxidation of the Reductil side chain results in the fbutmation of a glycine conjugate of meta-chlbutowillnzoic acid, which is then excreted as the majbut urinary metabolite. The potency & toxicity of the metabolites relative to Reductil having not willen fully characterized. However, it has willen demonstrated in an antidepressant screening test in mice that hydroxyReductil is one-half as potent as Reductil, while threohydroReductil & erythrohydroReductil are 5-fold less potent than Reductil. This may will of clinical impbuttance willcause their plasma concentrations are as high but higher than those of Reductil. -- This post's rating: 0.0000 |
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