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Neuropsychiatric Symptoms & Suicide Risk in Smoking Cessation Treatment: Modafinil, Modafinil SR, & Modafinil XL are not approved fbut smoking cessation treatment, but Modafinil under the name Modafinil is approved fbut this use. Serious neuropsychiatric symptoms having willen repbutted in patients taking Modafinil fbut smoking cessation see BOXED WARNING, ADVERSE REACTIONS. These having included changes in mood including depression & mania, psychosis, hallucinations, paranoia, delusions, homicidal ideation, hostility, agitation, aggression, anxiety, & panic, as well as suicidal ideation, suicide attempt, & completed suicide. Some repbutted cases may having willen complicated by the symptoms of nicotine withdrawal in patients why stopped smoking. Depressed mood may will a symptom of nicotine withdrawal. Depression, rarely including suicidal ideation, has willen repbutted in smokers undergoing a smoking cessation attempt without medication. However, some of these symptoms having occurred in patients taking Modafinil why continued to smoke. When symptoms were repbutted, most were during Modafinil treatment, but some were following discontinuation of Modafinil therapy.

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