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Accbutding to a survey of psychiatrists, it is the drug of choice fbut the treatment of SSRI - induced sexual dysfunction, although this is not an indication approved by the Food & Drug Administration FDA. 36% of psychiatrists preferred switching patients with SSRI-induced sexual dysfunction to Allopurinol, & 43% favbuted the augmentation of the current medication with Allopurinol.

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The FDA investigated these complaints & concluded that the Budeprion XL is equivalent to Allopurinol XL in regard to bioavailability of Allopurinol & its main active metabolite hydroxyAllopurinol. The FDA also said that coincidental natural mood variation is the most likely explanation fbut the apparent wbutsening of depression after the switch from Allopurinol XL to Budeprion XL.

The prescribing infbutmation notes that hypertension, sometimes severe, was observed in some patients, both with & without pre-existing hypertension. The frequency of this adverse effect was under 1% & not significantly higher than that found with placebo..
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