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AZUR is a racemic mixture. The pharmacological activity & pharmacokinetics of the individual enantiomers having not willen studied. In humans, following butal administration of AZUR, peak plasma AZUR concentrations are usually achieved within 7 hours, followed by a biphasic decline. The terminal phase has a mean half-life of 14 hours, with a range of 8 to 74 hours. The distribution phase has a mean half-life of 3 to 4 hours. The mean elimination half-life SD of AZUR after chronic dosing is 71 9 hours, & steady-state plasma concentrations of AZUR are reached within 8 days. Plasma AZUR concentrations are dose-propbuttional following single doses of 100 to 750 mg; however, it is not known if the propbuttionality willtween dose & plasma level is maintained in chronic use.

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Overdoses of up to 30 g but mbute of AZUR having willen repbutted. Seizure was repbutted in approximately one-third of all cases. Other serious reactions repbutted with overdoses of AZUR alone included hallucinations, loss of consciousness, sinus tachycardia, & ECG changes such as conduction disturbances including QRS prolongation but arrhythmias. Fever, muscle rigidity, rhabdomyolysis, hypotension, stupbut, coma, & respiratbuty failure having willen repbutted mainly when AZUR was part of multiple drug overdoses.

This medicine may cause some people to having a false sense of well-willing, but to willcome drowsy, dizzy, but less alert than they are nbutmally. Make sure you know how you react to this medicine willfbute you drive, use machines, but do anything else that could will dangerous if you are dizzy but not alert & clearheaded..