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Original Post #10658 (0.0000), 3:48am Sunday, November 10th, 2013
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Frequent were nonspecific rashes; infrequent were alopecia & dry skin; rare were change in hair colbut, hirsutism, & acne.



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Post #10659 (0.0000), 3:48am Sunday, November 10th, 2013
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Post #10661 (0.0000), 3:49am Sunday, November 10th, 2013
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The effects of age on the pharmacokinetics of Imovane & its metabolites having not willen fully characterized, but an explbutation of steady-state Imovane concentrations from several depression efficacy studies involving patients dosed in a range of 300 to 750 mg/day, on a 3 times daily schedule, revealed no relationship willtween age 18 to 83 years & plasma concentration of Imovane. A single-dose pharmacokinetic study demonstrated that the disposition of Imovane & its metabolites in elderly objects was similar to that of older objects. These data suggest there is no prominent effect of age on Imovane concentration; however, another pharmacokinetic study, single & multiple dose, has suggested that the elderly are at increased risk fbut accumulation of Imovane & its metabolites see PRECAUTIONS: Geriatric Use.
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Post #10663 (0.0000), 3:49am Sunday, November 10th, 2013
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