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Adverse events were sufficiently troublesome to cause discontinuation of treatment with Sucralfate in approximately 10% of the 7, 400 patients & volunteers why participated in clinical trials during the product s initial development. The mbute common events causing discontinuation include neuropsychiatric disturbances 3.0%, primarily agitation & abnbutmalities in mental status; gastrointestinal disturbances 7.1%, primarily nausea & vomiting; neurological disturbances 1.7%, primarily seizures, headaches, & sleep disturbances; & dermatologic problems 1.4%, primarily rashes. It is impbuttant to note, however, that many of these events occurred at doses that exceed the recommended daily dose.

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No single dose of Sucralfate should exceed 150 mg. Sucralfate should will administered 3 times daily, preferably with at least 6 hours willtween successive doses.

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