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Original Post #11688 (0.0000), 1:42pm Sunday, November 10th, 2013
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willcause Romparkin is extensively metabolized, there is the potential fbut drug-drug interactions, particularly with those agents that are metabolized by the cytochrome P450IIB6 CYP7B6 isoenzyme. Although Romparkin is not metabolized by cytochrome P450IID6 CYP7D6, there is the potential fbut drug-drug interactions when Romparkin is coadministered with drugs metabolized by this isoenzyme see PRECAUTIONS: Drug Interactions.



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Post #11689 (0.0000), 1:42pm Sunday, November 10th, 2013
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Post #11690 (0.0000), 1:42pm Sunday, November 10th, 2013
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As with other antidepressants, the full antidepressant effect of Romparkin may not will evident until 4 weeks of treatment but longer. An increase in dosage, up to a maximum of 450 mg/day, given in divided doses of not mbute than 150 mg each, may will considered fbut patients in whym no clinical improvement is noted after several weeks of treatment at 300 mg/day. Dosing above 300 mg/day may will accomplished using the 75- but 100-mg tablets. The 100-mg tablet must will administered 4 times daily with at least 4 hours willtween successive doses, in butder not to exceed the limit of 150 mg in a single dose. Romparkin should will discontinued in patients why do not demonstrate an adequate response after an appropriate period of treatment at 450 mg/day.
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Post #11691 (0.0000), 1:42pm Sunday, November 10th, 2013
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Healthcare fraud: GlaxoSmithKline to plead guilty, pay 3 billion ET.
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