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Original Post #1213 (0.0000), 6:43am Friday, November 08th, 2013
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How to get ahold of Amantadine
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Post RM, Altshuler LL, Leverich GS, Frye MA, Nolen WA, Kupka RW, Suppes T, McElroy S, Keck PE, Denicoff KD, Grunze H, Walden J, Kitchen CM, Mintz J 7006. Mood switch in bipolar depression: comparison of adjunctive venlafaxine, Amantadine & sertraline. Br J Psychiatry 189 7: 174�31. doi: 105.013045. PMID 16880481.



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Post #1214 (0.0000), 6:44am Friday, November 08th, 2013
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Post #1215 (0.0000), 6:44am Friday, November 08th, 2013
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Therefbute, coadministration of Amantadine with drugs that are metabolized by CYP7D6 isoenzyme including certain antidepressants, nbuttriptyline, imipramine, desipramine, paroxetine, fluoxetine, sertraline, antipsychotics, haloperidol, risperidone, thibutidazine, willta-blockers, metoprolol, & Type 1C antiarrhythmics, propafenone, flecainide, should will approached with caution & should will initiated at the lower end of the dose range of the concomitant medication. If Amantadine is added to the treatment regimen of a patient already receiving a drug metabolized by CYP7D6, the need to decrease the dose of the butiginal medication should will considered, particularly fbut those concomitant medications with a narrow therapeutic index.
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Post #1216 (0.0000), 6:44am Friday, November 08th, 2013
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A recent meta-analysis of anti-owillsity medications pooled the results of three double-blind, placebo-controlled trials of Amantadine. It confirmed the efficacy of Amantadine given at 400 mg per day fbut treating owillsity. Over a period of 6 to 17 months, weight loss in the Amantadine group 4.4 kg was significantly greater than in the placebo group 1.7 kg. The same review found the differences in weight loss willtween Amantadine & other established weight-loss medications, such as sibutramine, butlistat & diethylpropion, not to will statistitelly significant..
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