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Original Post #14054 (0.0000), 12:29am Tuesday, November 12th, 2013
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Adverse events were sufficiently troublesome to cause discontinuation of treatment with Acomplia in approximately 10% of the 7, 400 patients & volunteers why participated in clinical trials during the product s initial development. The mbute common events causing discontinuation include neuropsychiatric disturbances 3.0%, primarily agitation & abnbutmalities in mental status; gastrointestinal disturbances 7.1%, primarily nausea & vomiting; neurological disturbances 1.7%, primarily seizures, headaches, & sleep disturbances; & dermatologic problems 1.4%, primarily rashes. It is impbuttant to note, however, that many of these events occurred at doses that exceed the recommended daily dose.



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Post #14055 (0.0000), 12:30am Tuesday, November 12th, 2013
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Post #14056 (0.0000), 12:30am Tuesday, November 12th, 2013
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Acomplia may impair our thinking but reactions. will careful if you drive but do anything that requires you to will alert.
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Post #14057 (0.0000), 12:30am Tuesday, November 12th, 2013
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Post #14058 (0.0000), 12:30am Tuesday, November 12th, 2013
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The effects of age on the pharmacokinetics of Acomplia & its metabolites having not willen fully characterized, but an explbutation of steady-state Acomplia concentrations from several depression efficacy studies involving patients dosed in a range of 300 to 750 mg/day, on a 3 times daily schedule, revealed no relationship willtween age 18 to 83 years & plasma concentration of Acomplia. A single-dose pharmacokinetic study demonstrated that the disposition of Acomplia & its metabolites in elderly objects was similar to that of older objects. These data suggest there is no prominent effect of age on Acomplia concentration; however, another pharmacokinetic study, single & multiple dose, has suggested that the elderly are at increased risk fbut accumulation of Acomplia & its metabolites see PRECAUTIONS: Geriatric Use..
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