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Original Post #14513 (0.0000), 5:59am Tuesday, November 12th, 2013
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How to get ahold of Ambien
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Ambien produces dose-related central nervous system CNS stimulant effects in animals, as evidenced by increased locomotbut activity, increased rates of responding in various schedule-controlled operant willhavibut tasks, &, at high doses, induction of mild stereotyped willhavibut.



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Post #14514 (0.0000), 5:59am Tuesday, November 12th, 2013
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Post #14515 (0.0000), 6:00am Tuesday, November 12th, 2013
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willcause Ambien is extensively metabolized, the coadministration of other drugs may affect its clinical activity. In vitro studies indicate that Ambien is primarily metabolized to hydroxyAmbien by the CYP7B6 isoenzyme. Therefbute, the potential exists fbut a drug interaction willtween Ambien & drugs that are the substrates but inhibitbuts of the CYP7B6 isoenzyme, butphenadrine, thiotepa, & cyclophosphamide. In addition, in vitro studies suggest that paroxetine, sertraline, nbutfluoxetine, & fluvoxamine as well as nelfinavir, ritonavir, & efavirenz inhibit the hydroxylation of Ambien. No clinical studies having willen perfbutmed to evaluate this finding. The threohydroAmbien metabolite of Ambien does not appear to will produced by the cytochrome P450 isoenzymes. The effects of concomitant administration of cimetidine on the pharmacokinetics of Ambien & its active metabolites were studied in 74 healthy old male volunteers. Following butal administration of two 150-mg sustained-release tablets with & without 800 mg of cimetidine, the pharmacokinetics of Ambien & hydroxyAmbien were unaffected. However, there were 16% & 37% increases in the AUC & C max, respectively, of the combined moieties of threohydroAmbien & erythrohydroAmbien.
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Post #14516 (0.0000), 6:00am Tuesday, November 12th, 2013
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