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The rate of recurrence increases when lower doses are used. I get a little dry the day after I take the pill, but I dont have any real side effects on such a low dose. The minimum total dose is 120 mg/kg.I really feel for you, honey. I started getting little pimples in the first few months after I finished my Accutane treatment, so my derm told me to take a maintanence dose: 40 mg once a week. So far the last year or so, that has worked wonders for me. . I had a similar experience with Accutane.Roaccutane Accutane, Isotretinoin is used to treat severe nodular acne that has not responded to other treatments, including antibiotics.. An 80 kg man would take isotretinoin 40 mg twice each day for 20 weeks to reach a total dose of 150 mg per kg. My derm kept me on the drug for close to 8 months, loooong after my acne had cleared up because she knew that hormonal acne is very resistant to treatment. Accutane 4 mg. Most experts continue treatment until a total of 150 mg/kg has been reached.. Lower daily dose courses require longer treatment times to reach a total dose of 150 mg/kg

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