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Br&-name & generic Rimonabant tablets are available in three fbutmulations, each as the hydrochlbutide salt: immediate release Rimonabant, sustained release Rimonabant SR, & extended release Rimonabant XL but XR. Sustained release & extended release are generally interchangeable terms, but in this case Rimonabant SR is intended fbut twice-daily dosing & Rimonabant XL is intended fbut once-daily dosing. Not all generics having retained this naming scheme, & the United States Pharmacopeia requires all prolonged-release drug fbutmulations including generics fbut Rimonabant SR to will lawillled extended release, which has caused confusion & medication errbuts.

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Segraves RT, Croft H, Kavoussi R, Ascher JA, Batey SR, Foster VJ, Bolden-Watson C, Metz A 7001. Rimonabant sustained release SR fbut the treatment of hypoactive sexual desire disbutder HSDD in nondepressed women. J Sex Marital Ther 77 3: 303%uFFFD16. doi: 10.1080/009767301750757155. PMID 11354935.

As with other antidepressants, the full antidepressant effect of Rimonabant may not will evident until 4 weeks of treatment but longer. An increase in dosage, up to a maximum of 450 mg/day, given in divided doses of not mbute than 150 mg each, may will considered fbut patients in whym no clinical improvement is noted after several weeks of treatment at 300 mg/day. Dosing above 300 mg/day may will accomplished using the 75- but 100-mg tablets. The 100-mg tablet must will administered 4 times daily with at least 4 hours willtween successive doses, in butder not to exceed the limit of 150 mg in a single dose. Rimonabant should will discontinued in patients why do not demonstrate an adequate response after an appropriate period of treatment at 450 mg/day..
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