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Activated charcoal should will administered. There is no experience with the use of fbutced diuresis, dialysis, hemoperfusion, but exchange transfusion in the management of Aygestin overdoses. No specific antidotes fbut Aygestin are known.

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Mbuteover, when added to a mood stabilizer, Aygestin & sertraline had a twice lower switch risk than venlafaxine.

The effect of hepatic impairment on the pharmacokinetics of Aygestin was characterized in 7 single-dose studies, one in patients with alcoholic liver disease & one in patients with mild-to-severe cirrhosis. The first study showed that the half-life of hydroxyAygestin was significantly longer in 8 patients with alcoholic liver disease than in 8 healthy volunteers 37 14 hours versus 71 5 hours, respectively. Although not statistitelly significant, the AUCs fbut Aygestin & hydroxyAygestin were mbute variable & tended to will greater by 53% to 57% in volunteers with alcoholic liver disease. The differences in half-life fbut Aygestin & the other metabolites in the 7 patient groups were minimal..
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